Research on antithrombotic effect of total saponins of Astragalus
- VernacularTitle:黄芪总皂苷抗血栓形成作用实验研究
- Author:
Jian GAO
;
Xianxiang XU
;
Xianjun XU
;
Shoudong NI
;
- Publication Type:Journal Article
- Keywords:
total saponins of astragalus;
thrombosis;
TXA 2;
PGI 2;
NO
- From:
Chinese Traditional Patent Medicine
1992;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To research antithrombotic effect and mechanism of total saponins of Astragalus (TSA).Methods: Effects of TSA on artery thrombosis anud platelet aggregation were studied, at dosage of 50,100,200mg/kg. And level of TXA 2,PGI 2 in plasma, content of NO in serum of rats were determined.Results: TSA could restrain artery thrombosis and platelet aggregation of rats, and increase PGI 2 and NO.Conclusion: There was apparently antithrombotic effect of TSA.
