TOPOGRAPHIC CHARACTERISTICS OF THE PROLIFERATION ACTIVITY OF KERATINOCYTES IN EPIDERMIS OF RATS
- VernacularTitle:大鼠表皮角化细胞增殖活性的拓扑学特点
- Author:
Hongmei HAN
;
Jingyu FAN
;
- Publication Type:Journal Article
- Keywords:
Keratinocyte;
Proliferation activity;
Nucleolar organizer regions;
Proliferating cell nuclear antigen;
Rat
- From:
Acta Anatomica Sinica
1953;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study topographic characters of the proliferation activity of keratinocytes on the fore limbs of rats and to explore the relationship beween these characters and meridians. Methods By routine paraffin section,silver staining technique for NOR and immunohistochemical techniques of PCNA were used to study topographic characters of the proliferation activity of keratinocytes. Results The proliferation activity of keratinocytes on the fore limbs of rats is different according to the locations on the horizonal direction,and the keratinocytes with low proliferation activity are clustered into groups,the scale of which is about 10 -3 m.As result,3 4 ribbons of keratinocytes with low proliferation activity are formed on the vertical direction,where 3 4 meridians are supposed to be the positions of the comparative anatomy.Conclusion\ This study suggested that the keratinocytes on the meridians are characteritic of the low proliferation activity.\;[
