Analgesic Effect of Yunzhi Polysaccharopeptide and Preliminary Analysis of Its Mechanism
- VernacularTitle:云芝糖肽的镇痛作用及其机理的初步分析
- Author:
Weiping YIN
;
Shan GONG
;
Xinghong JIANG
;
Zhenlun GU
;
- Publication Type:Journal Article
- Keywords:
coriolus versicolor;
analgesia;
hot plate test;
electrical stimulation vocalization test;
mediobasal hypothalamus.
- From:
Chinese Traditional Patent Medicine
1992;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the analgesic effect of Yunzhi polysaccharopeptide (PSP) and analyze its mechanism. Methods: The hot plate test in mice and the tail stimulation vocalization test in rats were used.Results: PSP administered po at a dose of 1.0 g/kg for 7 days could produce a significant analgesic effect, which could last for more than two hours. The analgesic effect of PSP disappeared after lesion of mediobasal hypothalamus. Conclusions: PSP could elicit a central analgesic effect.
