Effect of rehmaionoside A on cyclophosphamide induced leukopenia in mice
- VernacularTitle:地黄苷A对环磷酰胺致小鼠白细胞减少症的影响
- Author:
Zhen YU
;
Jun WANG
;
Gengsheng LI
;
Yusheng WANG
;
- Publication Type:Journal Article
- Keywords:
rehmaionoside A;
cyclophosphamide;
leukopenia;
leukogenic action
- From:
Chinese Traditional and Herbal Drugs
1994;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Object To observe the effects of rehmaionoside A on mice leukopenia models induced by cyclophosphamide. Methods Mice leukopenia models were prepared by ip cyclophosphamide and then treated with rehmaionoside A. The levels of body weight, peripheral hemogram, reticulocyte count, spleen index, bone marrow karyocyte count and contents of bone marrow DNA were determined. Results Rehmaionoside A could obviously raise the counts of white blood cell, red blood cell, platelet, reticulocyte and bone marrow karyocyte, contents of bone marrow DNA, and body weight of the leukopenia model. Conclusion Rehmaionoside A has apparent leukogenic and antianemic actions.
