Effect of Alcohol Concentration of Shangtong Tincture on Percutaneous Absorption of Paeonol
- VernacularTitle:伤痛酊乙醇浓度对丹皮酚透皮吸收的影响
- Author:
Chunhai LIU
;
Yonghua YANG
;
Shuihan ZHANG
;
- Publication Type:Journal Article
- Keywords:
Shangtong Tincture;
percutaneous absorption;
paeonol;
HPLC
- From:
Chinese Traditional Patent Medicine
1992;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To select the optimum alcohol concentration of Shangtong Tincture. Methods: The percutaneous absorption test was performed on excised rats skin in improved Franz diffusion cell. The penetrative amount of paeonol was determined quantitatively by HPLC and the content of paeonol as a marker. Results: The penetrative amount of paeonol of Shangtong Tincture with 60%～80% alcohol concentration have a optimal value, the average rate is 0.010mg/cm 2?h. Conclusion: Shangtong Tincture with 70% alcohol concentration is the best.
