Effect of Liuweidihuang Pills on Neural Sorbitol in Alloxan Diabetic Rats
- VernacularTitle:六味地黄丸对糖尿病大鼠坐骨神经山梨醇含量的影响
- Author:
Ping LIANG
;
Zuopeng QI
;
- Publication Type:Journal Article
- Keywords:
Liuweidihuang Pills;
sorbitol;
diabetic neuropathy;
rat
- From:
Chinese Traditional Patent Medicine
1992;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the mechanism of the effect of Linweidihuang Pills on diabetic neuropathy in rat. Methods: The diabetic rats were induced by alloxan. Serum glucose was tested by glucose oxidase and sciatic nerve sorbitol was determined by GC. Results: After Liuweidihuang Pills,0.5～2g/kg taken orally for 3 months, the level of sciatic nervous sorbitol and serum glucose in rat decreased significantly and the results showed certain dose effect relationship.Conclusion: Liuweidihuang Pills can controll diabetic neuropathy by inhibiting sorbitol biosynthesis.
