Studies on anti-inflammatory and antiallergic effects of CH_2Cl_2 extract of Flos Magnoliae
- VernacularTitle:辛夷二氯甲烷提取物抗炎、抗过敏作用研究
- Author:
Yongzhong ZHANG
;
Xiaoli LI
;
Guangmin MOU
;
- Publication Type:Journal Article
- Keywords:
CH 2Cl 2 extract of Flos Magnoliae;
anti inflammatory;
antiallergy;
inflammatory mediator
- From:
Chinese Traditional and Herbal Drugs
1994;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Object To study the pharmacological effects of CH 2Cl 2 extract of Flos Magnoliae.Methods Anti inflammatory and antiallergic effects of CH 2Cl 2 extract of Flos Magnoliae were studied on various experimental models. Results The extract remarkably inhibited the contraction caused by histamine and acetylcholine, as well as the ovalbumin sensitized allergic constriction of isolated ileum smooth muscle of guinea pigs. It could inhibit the increase of capillary permeability induced by acetic acid in mice, inhibit the mice paw edema produced by carrageenin and reduce the production of PGE 2 in inflammatory tissues. Conclusion CH 2Cl 2 extract of Flos Magnoliae showed remarkable anti inflammatory and antiallergic effects.
