A Study on Releasing Rule of Artesunate TDD System
- VernacularTitle:青蒿琥酯贴片的释放行为研究
- Author:
Haixia HOU
;
Liling ZHOU
;
Rui LI
;
- Publication Type:Journal Article
- Keywords:
Artesunate TDDs;
accumulative releasing ratio;
releasing speed;
Higuchi equation;
durable effect
- From:
Chinese Traditional Patent Medicine
1992;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the releasing rule of Artesunate TDD s (ASTDDs). Methods: To prepare the ASTDDS and determine the content of artesunate, the transdermal experiments are used to study the relation between accumulative releasing ratio or releasing speed and releasing time. Results: The content of artesunate is about 45mg/10cm 2 and the accumulative releasing ratio increases with releasing time, but releasing speed is constant when the releasing speed reached some value. Conclusion: The releasing rule of ASTDDs conforms to Higuchi equation. The ASTDDs can come to durable effect.
