Determination of Acetamidopyrrolidone in Compound Huonaosu Capsules by RP-HPLC
- VernacularTitle:RP-HPLC测定复方活脑素胶囊中吡拉西坦的含量
- Author:
Chunxiang ZHAO
;
Zhuosong JIANG
;
Chunshi LI
;
Qiuming RU
;
Guijie ZHANG
;
Lianxiu ZHENG
;
- Publication Type:Journal Article
- Keywords:
acetamidopyrrolidone;
Compound Huonaosu Capsules;
HPLC
- From:
Chinese Traditional Patent Medicine
1992;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To establish the determination method of acetamidopyrrolidone in Compound Huonaosu Capsules with RP HPLC. Methods: Kromasil C 18 column was used. The mobile phase was methanol water(10∶90) with 0.6ml?min -1 of flow rate, and the detection wavelength was at 230nm. Results: The linear range of acetamidopyrrolidone concentration was from 0.17 to 0.78mg?ml -1 and correlation coefficient was 0.9995. The average recovery of sample was 99.9% and RSD and 0.62%(n=5). Conclusion: The method is simple, accurate and reproducible. It can be used for determination of acetamidopyrrolidone Compound in Huonaosu Capsules.
