Effect of Baihuzhuifeng Pills on Interlukin-1? Secreted by Synoviocyte in Adjuvant Arthritis Rats
- VernacularTitle:白虎追风丸对大鼠佐剂性关节炎滑膜细胞分泌IL-1?的影响
- Author:
Xuguang SHI
;
Shengpeng ZHANG
;
Zhidong XU
;
- Publication Type:Journal Article
- Keywords:
adjuvant arthritis;
synovial membrane;
cell culature;
interlukin 1?;
Baihuzhufeng Pills
- From:
Chinese Traditional Patent Medicine
1992;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the effect of Baihuzhuifeng Pills (BHZFP) on interleukin 1?(IL 1?) secreted by synoviocytes in adjuvant arthritis (AA) rats. Methods: Synovium of knee joints from AA rats were digested by collagenase and tripsin to prepare DSSC(digested synovial single cells). The content of the supernatant fluid was assayed by the radioimmunoassay. Results: BHZFP down regulated IL 1? productions of DSSC.Conclusion: It is suggested that BHZFP be probably inhibit the over proliferation of synoviocyte in AA rats by diminishing IL 1? secretion.
