Experimental Study on Effect of Shexiangbaoxin Pills on Morphosis and Function of Left Ventricle after Myocardial Infarction in Rat
- VernacularTitle:麝香保心丸对心肌梗塞后左室形态和功能影响的实验研究
- Author:
Xinping LUO
;
Haiming SHI
;
Zhiyu ZENG
;
Weihu FAN
;
Shouyi WANG
;
Ruihong DAI
;
- Publication Type:Journal Article
- Keywords:
Shexiangbaoxin Pills;
myocardial infarction,morphology;
cardiac function
- From:
Chinese Traditional Patent Medicine
1992;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the effect of Shexiangbaoxin Pills on morphosis and function of left ventricle after myocardial infarction in rat. Methods: The rat myocardial infarction models induced by ligaturing coronary artery were randomly divided into the myocardial infarction control group, Shexiangbaoxin Pill group and captopril group. The hemodynamic parameters and cardiac functions in 2 or 6 weeks after treatment were determined. Meantime, the morphological parameters of left ventrile (left cardiac chamber size, attenuation proportion of ventricular wall of infarction area, and expansion index of left ventrile), were studied. Results: Shexiangbaoxin Pills could reduce the distention of left ventrile and expansion of infarction area of rat in 6 weeks after infarction. It could obviously improve the contraction function of left ventrile after myocardial infarction. Conclusion: Shexiangbaoxin Pills can improve left ventricular reconstitution after myocardial infarction.
