Experimental Study on Shenduqing Granules on Chronic Renal Insufficiency
- VernacularTitle:肾毒清冲剂治疗慢性肾功能不全的实验研究
- Author:
Xiuli GUO
;
Jianbo JI
;
Xinwen JING
;
Zhao HU
;
Yong ZHOU
;
- Publication Type:Journal Article
- Keywords:
Shenduqing Granules;
chronic renal insufficiency;
creatinine;
blood urea nitrogen;
calcium;
glomerulus
- From:
Chinese Traditional Patent Medicine
1992;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the protective effect of shenduqing Granules on chronic renal insufficiency in rats. Methods: The rat model of chronic renal insufficiency was made by feeding 0.75% adenine forage. The blood biochemical indexes, ion concentration in serum of rat was measured and the pathological changes of rat kidney were observed. Results: Shenduqing Granules obviously increased thymus index (TI). The weight of rat kidney in the treatment group was lighter than that of the model group. The kidney histomorphological study showed that Shenduqing Granules obvionsly reduce the pathological changes. The drug crystals were also reduced. Conclusion: Shenduqing Granules has the potential protection against chronic renal insufficiency in rats.