Isolation and identification of new components in mother liquor of synthetic dihydroartemisinin methyl ether
- VernacularTitle:蒿甲醚合成母液中一个新成分的分离和鉴定
- Author:
Xiaotian XIE
;
Ping ZHENG
;
Guangyao ZHANG
;
Minghui YANG
;
- Publication Type:Journal Article
- Keywords:
dihydroartemisinin methyl ether;
chromatographic separation;
12 deoxy 11 enartemisinin
- From:
Chinese Traditional and Herbal Drugs
1994;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Object To isolate and identify the artemisinin like impurities present in the mother liquor of synthetic dihydro artemisinin methyl ether, for the development of new drugs Methods Artemisinin like compounds in the synthetic mother liquor were isolated by chromatography Results 5 compounds were isolated and identified They were ? dihydroartemisinin methyl ether (Ⅰ); ?, 12 deoxy artemisinin 12 ol (Ⅱ); artemisinin (Ⅲ); octahydro 8 methoxy 4, 7 dimethyl furo benzopyran 10 yl acetate (Ⅳ) and 12 deoxy 11 en artemisinin (Ⅴ) Conclusion Compound Ⅴ was new
