Effects of gypenosides on monoamine oxidase and Na/K-ATPase activities in brain tissues of aging mice
- VernacularTitle:绞股蓝总苷对老化小鼠脑中MAO和Na/K-ATP酶活性的影响
- Author:
Guoqing GONG
;
Zhiyu QIAN
;
Shu ZHOU
;
- Publication Type:Journal Article
- Keywords:
gypenosides;
aging mice;
monoamine oxidase;
Na/K ATPase
- From:
Chinese Traditional and Herbal Drugs
1994;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Object To study the effects of gypenosides on MAO and Na/K ATPase activities in brain tissues of aging mice Methods Models of aging mice were prepared by continuous post orbitol injection of 120 mg/kg D galactose for a month, then the effects of gypenosides on MAO and Na/K ATPase activities in brain tissues were investigated Results It was observed that MAO activity was increased and Na/K ATPase activity was decreased in brain tissues of aging mice models significantly; and these effects were reversible respectively by gypenosides ig of 75 and 150 mg/kg Conclusion The result that gypenosides could invert the changes of MAO and Na/K ATPase activities in brain tissues of aging mice, may provide a further explaination of the anti aging mechanism of gypenosides in molecule enzymology
