Peritoneal Metastatic Goblet-Cell Carcinoid Tumor Treated With Cytoreductive Surgery and Intraperitoneal Chemotherapy.
- Author:
Sang Il YOUN
1
;
Hwan NAMGUNG
;
Jeong Seok YUN
;
Yun Jun PARK
;
Dong Guk PARK
Author Information
- Publication Type:Case Report
- Keywords: Appendix; Carcinoid tumor; Goblet cells; Peritoneal neoplasms; Intraperitoneal infusion
- MeSH: Abdomen; Adenocarcinoma; Appendix; Carcinoid Tumor*; Colonoscopy; Constipation; Diagnosis; Drug Therapy*; Goblet Cells; Humans; Infusions, Parenteral; Male; Middle Aged; Neoplasm Metastasis; Peritoneal Neoplasms; Peritoneum; Rabeprazole; Rectum
- From:Annals of Coloproctology 2015;31(2):74-78
- CountryRepublic of Korea
- Language:English
- Abstract: We report a case of a goblet-cell carcinoid tumor of the appendix which metastasized to the peritoneum and was treated by using cytoreductive surgery (CRS) with intraperitoneal chemotherapy. A 47-year-old male presented with chronic constipation and was diagnosed as having a rectal adenocarcinoma with a signet-ring-cell component under colonoscopy. Computed tomography suggested peritoneal metastases with diffuse nodular parietal peritoneal thickening of the entire abdomen and focal invasion of the upper rectum by a seeding mass. CRS with intraperitoneal chemotherapy was done under the diagnosis of a rectal adenocarcinoma with peritoneal metastases. The pathologic diagnosis was a goblet-cell carcinoid tumor of the appendix with peritoneal metastasis. The histological discrepancy between a peritoneal metastatic mass and a rectal mass was due to the mixed histological pattern of a goblet-cell carcinoid tumor. A metastatic mass may not share identical immunohistochemical characteristics from its origin. This histologic discrepancy necessitates caution in diagnosing a distant metastasis of a goblet-cell carcinoid tumor.