Opioid pharmacogenetics in anesthesia and pain management.
10.17085/apm.2015.10.2.65
- Author:
Kye Min KIM
1
Author Information
1. Department of Anesthesiology and Pain Medicine, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea. kyemin@paik.ac.kr
- Publication Type:Review
- Keywords:
Analgesia;
Anesthesia;
Opioid;
Pharmacogenetics
- MeSH:
Analgesia;
Analgesics, Opioid;
Anesthesia*;
Humans;
Pain Management*;
Pharmacogenetics*
- From:Anesthesia and Pain Medicine
2015;10(2):65-76
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Opioids are the cornerstone for treating moderate to severe pain and are commonly used for anesthesia and pain management. However, large inter-individual variability exists in the analgesic and adverse effects. It would be very helpful to predict the opioid response of each patient, considering the serious outcomes related to insufficient pain control and fatal side effects. Pharmacogenetic data on opioids have accumulated; thus, the aim of this article is to review the pharmacogenetic studies related to opioids frequently used for anesthesia and pain management.
