Effect of Fuyuanbunao Granules on Memory of Experimental Mice
- VernacularTitle:扶元补脑冲剂对实验小鼠记忆的影响
- Author:
Yongqi LIU
;
Jiancheng HE
;
Xiong LIU
;
Houqian XU
;
Zhenggang SHI
;
- Publication Type:Journal Article
- Keywords:
Fuyuanbunao Granules;
memory;
acute toxicity test
- From:
Chinese Traditional Patent Medicine
1992;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To probe and reveal the brain tomic and the wise sharpening action of Fuyuanbunao Granules and Its toxicity and side effect. Methods: The effects of Fuyuanbunao Granules on the memory acquisition disturbance induced by pentobarbital sodium or anisodine, the memory consolidation disturbance induced by sodium nitrite, and the memory repetition disturbance induced by alcohol were observed. Meanwhile, the acute toxicity test was done. Results: The granules could obriously improve the memory disturbance induced by the factors obove, and the improvement effect varied with the dose. The effects of larger dose groups were more obvious. There were no death of animals or toxicity and sile effect in test. Conclusion:Fuyuanbunao Granules maybe have the cholinergic acction. It can promote the aerobic metabolism, improve the cerebral anoxia and the inhibited state of center nervous system. It has low toxicity and can be used in clinical application.
