A Clinical Study On Vindesine in the Interventional Treatment of Hepatic and Pulmonary Carcinomas
- VernacularTitle:西艾克介入性治疗肝癌、肺癌的临床研究
- Author:
Shijie SHI
;
Ying ZHAN
;
Dong JIANG
;
Gun LING
;
- Publication Type:Journal Article
- Keywords:
Liver cancer;
Lung cancer;
Tumar of liver
- From:
Journal of Interventional Radiology
1992;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Purpose:To evaluate the efficacy and toxicity of vindercine(VDS)in the interven- tional treatment of hepatic and pulmonary carcinomas.Materials and Methods:30 cases of mid-ad- vanced hepatic and pulmonary carcinomas,among them,13 eases of primary hepatic carcinomas,7 cases of matastic hepatic carinomas and 10 cases of primary pulmonary carcinomas,were treated by selective arterial infusion chemotherapy.The combination chemotherapeutic regimens conpored of VDS together with 5-Fu,MMC,carboplatin or Vp16.Results:The response rate for all cases was 60%,for primary hepatic carcinomas 61.5%,for metastic hepatic carcinoma 42.9% and for primary pulmonary carcinoma 70%.Myelosuppession was the main toxicity and 70% patients had the gastrointertional reac- tions as nusea,vomiting etc.Conclusion:VSD is a more effective drug for pulmonary carcinoma,but for hepatic carcinoma,the efficacy of VDS was unmarkable from other drugs.
