Experimental Study on Pharmacology and Toxicology of Baizi Yangxin Pian
- VernacularTitle:柏子养心片药理、毒理学实验研究
- Author:
Guihai LI
;
Jianwei ZHU
;
Mingxia LIU
;
- Publication Type:Journal Article
- Keywords:
BAIZI YANGXIN WAN/pharmacology@BAIZI YANGXIN PlAN/pharmacology@BAIZI YANGXIN PIAN/toxicity SLEEP/drug effects ANIMAL MICE
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
1993;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Baizi Yangxin Pian is a reformed preparation of Baizi Yangxin Wan (bolus) listed in the Pharmacopoeia of People's Republic of China and is considered as a new drug of 4th class. According to the requirement of Regulations for New Drug Approval, its pharmacodynamics and acute and long-term toxicity tests were observed. It was shown that this preparation has a tranquilizing effect which is stronger than Baizi Yahgxin W an. LD_(50) is greater than 37.5g/kg. No toxic effect is revealed in rats after its long-term administration (9g/kg, 4.5g/kg and 3g/kg).