EFFECT OF FUFANG GANNING ON PROTECTING LIVER AND ENHANCING IMMUNITY
- VernacularTitle:复方肝宁保肝及提高免疫功能的作用
- Author:
Xiangzhong ZHENG
;
Feng NI
;
Biying WANG
;
- Publication Type:Journal Article
- Keywords:
@FUFANG GANNING/pharmacology;
LIYER/drug effects;
LIVER/physiopathology;
HEPATITIS;
TOXIC/chemically induced;
DISEASE MODELS;
ANIMAL;
RATS;
MICE
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
1993;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Fufang Ganning(FGN)is an oral liquid,consisting of 8 kinds of chinese herbs including Radix Astragali,Radix Salviae Multiorrhizae,Radix Curcumae,Rhizoma Polygonati,etc.It was found to be effective in protecting against experimental acute hepatic damage caused by CC14,TAA and D-Glan in mice,FGN could reduce ALT and retention of BSP,and histopathological chan- ges revealed that the hepatic injury induced by CC14 in animals received FGN was much less severe than those of the control ones.It could also lower ALT and serum bilirubin in mouse and rat models with hepatic injury caused by ?- isothioeyanate.On the other hand,in the animal models with cirrhosis induced by CC14,FGN could not only cut down ALT but also lessen the degeneration and necrosis of hepatic cells and cirrhotic changes.Meanwhile,FGN could significantly increase the clearance index of carbon particles(phagocytic func- tion)and serum hemolysin in normal mice.It is concluded that FGN has the effects of protecting liver from damage and enhancing the immune function.
