A STUDY ON THE DISTRIBUTION,ORIGIN AND PROPERTIES OF GALANIN IN SMALL INTESTINE OF RATS
- VernacularTitle:大鼠小肠甘丙素分布、来源及性质的研究
- Author:
Ping LIU
;
Wenqin CAI
;
- Publication Type:Journal Article
- Keywords:
Rat;
Small intestine;
Galanin;
immunocytochemistry
- From:
Acta Anatomica Sinica
1989;0(S1):-
- CountryChina
- Language:Chinese
-
Abstract:
The characteristics of distribution, origin and properties of galanin (GAL) were investigated, by using immunocytochemistry (the whole mount stretched pr- eparations and cryostat sections), immunoelectronmicroscopy and microspectroph- ometer measuring techniques. The results showed that (1) All layers of small intestine were rich in GAL- immunoreactive(GAL-I) nerves with a high density in myenteric and submucosal plexuses. (2) A rather high density around the small blood vessels of the small intestine and intestinal crypts were observed. Some GAL-I neurons were seen in the myenteric and submucosal plexuses. Enteric GAL-I nerve fibers seemed to be endogenic and probably related to the regulation of motor function in the gastro- intestinal tract, since there was no obvious reducation of nerve fibers after sec- tion of mesenterium or injection of capsaicin. (3) The distribution and charac- teristics of GAL-I nerve fibers in small intestine indicated that the GAL-I ne- rves might be playing a regulational role in the motion, absorption, secretion and regional blood flow of the gastrointestinal tract.
