DISTRIBUTION OF MONOAMINERGIC AND SOME PEPTIDERGIC AFFERENT FIBERS IN THE INTERMEDIATE ZONE OF THE RAT SPINAL CORD
- VernacularTitle:大鼠脊髓中间带内单胺能和某些肽能传入纤维的分布特征
- Author:
Lixin WANG
;
Peilin ZHANG
;
- Publication Type:Journal Article
- Keywords:
Intermediate zone of the spinal cord;
Immunocytochemistry;
Tyrosine hydroxylase;
5-hydroxytryptamine;
Substance P;
Leucine-enkephalin;
Oxytocin;
Rats
- From:
Acta Anatomica Sinica
1957;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
This study demonstrated with the immunocytochemical ABC method that thedistribution pattern of TH,5-TH,SP,L-ENK and OXY immunoreactive fiberswere alike in the intermediate zone of the thoracic and upper lumbar spinal cord.These fibers located in the lateral funiculus,lateral horn,intermediate gray and thearea surrounding the central canal,forming a transversal fiber band with most ofthe fibers in the lateral horn.In the lateral horn,TH,5-HT,SP and L-ENKimmunoreactive fibers and terminals aggregated in fiber clusters and numerous fib-ers made up a longitudinal bundle running through the fiber clusters.These immuno-reative fibers and terminals surrounding the central canal and distributed mainly dorsalto it.TH and 5-HT fibers accumulated in midplane where some fibers ran in alongitudinal fiber bundle and bilateral fibers and terminals distributed sparsely.SP and L-ENK fibers and terminals were relatively less in the midplane whiledense laterally.All kinds of the immunoreactive fibers were found close to theependyma.Two small 5-HT fiber bundles ran parallel and lateral to the centralcanal and a small SP fiber bundle ventral to it.Moderate immunoreactive fiberswere found periodically in the intermediate gray and formed distinct bands to linkfiber clusters in the lateral horn and fibers dorsal to the central canal.The imm- unoreactive fibers in lateral funiculus accumulated near the lateral horn and mostdensely in upper thoracic cord.OXY-containing fibers were much less than theothers,thus obvious fiber clusters,longitudinal bundle or transversal bands had notbeen found.In general,the distribution pattern of some monoaminergic and pepti-dergic fibers in the intermediate zone was provided with a laddershaped configura-tion.The two longitudinal immunoreactive fiber bundles——dorsal to the centralcanal and within the lateral horn,located medial and lateral in the spinal grayrespectively,and the transversal bands appeared periodically in the intermediate graybridging between the two longitudinal bundles.This configuration of immunorea-ctive fibers coincided with nuclear regions which contained preganglionic sympatheticneurons as well as their dendrites.