AGE CHANGES OF RNA,LIPOFUSCIN,NUCLEOLAR VOLUME AND NUMBER OF NEURONS IN HIPPOCAMPAL CA_3 AREA OF RATS
- VernacularTitle:海马 CA_3区神经元的 RNA、衰老色素、核仁体积和细胞数的年龄变化
- Author:
Zhibin YAO
;
Yici CHEN
;
Guobi KUANG
;
Luming YE
;
- Publication Type:Journal Article
- Keywords:
Neurons in hippocampus;
Aging;
RNA;
Lipofuscin
- From:
Acta Anatomica Sinica
1957;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
The methods of morphometry,histologic fluorescence quantification and quantita-tive histochemistry,RNA content,lipofuscin (Lp) content,nucleolar volume andneuron number (cells/250?m) were applied in the study of neurons in hippocampalCA_3 area in 4 age groups of Wistar rats (1,3,17,30 months).RNA content,nucleolar volume and neuron number decrease with advancingage.The difference between adult (17 months) and aged (30 months) rats weresignificant (P