IMMUNOELECTRON MICROSCOPIC STUDY OF PEPTIDE SUBSTANCES IN THE RAT NEUROHYPOPHYSIS
- VernacularTitle:大鼠神经垂体肽类物质的免疫电镜研究
- Author:
Changgeng ZHU
;
Aqing CHEN
;
Qingying LIU
;
Ying WEI
;
Xuanlin PENG
;
- Publication Type:Journal Article
- Keywords:
Neurohypophysis;
Peptide;
Axo-Axonic synapses;
Pituicytes;
Immunoelectron microscopy
- From:
Acta Anatomica Sinica
1954;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
The ultrastructural localization of peptide substances——VP,SP,ENK,SRIFand distribution of peptidergic nerves in rat neurohypophysis were studied by elect-ron microscopy.The results showed that VP,SP,ENK and SRIF immunoreactiveproducts located in large granular vesicles(110-150 nm in diameter),at the surfaceof microvesicles and outer membrane of mitochondria.The VP-,SP-,ENK- andSRIF-containing nerve fibers distributed at periphery of capillaries and vicinity ofpituicytes.VP- and ENK- positive nerve terminals formed axo-axonic synapses withnegative terminals.Axo-axonic synapses also existed between two SRIF-positive ter-minals.In addition,ENK- and SP-positive terminals formed synaptoid structureswith pituicytes.The authors have discovered the VP-positive pituicytes for the firsttime.The scientific significances of present paper are as follows:(1)Several kinds ofpeptide such as VP,SP,ENK and SRIF have been identified in neurohypophysis atultrastructural level;(2)The discovery of VP-positive pituicytes and their peptide-rgic innervation imply that these structures probably participate in the regulation ofneurohormone releasing;(3)New morphological bases have been provided for theregulation of neurohormone releasing.
