EFFECT OF LIFE STYLE COMBINED WITH DIETARY INTERVENTION ON NON-ALCOHOLIC FATTY LIVER DISEASE
- VernacularTitle:对非酒精性脂肪肝患者生活方式结合膳食干预的效果观察
- Author:
Feifei GUAN
;
Rongxiu WU
;
Wei LIU
;
- Publication Type:Journal Article
- Keywords:
overweight;
non-alcoholic fatty liver disease;
exercise;
dietary intervention
- From:
Acta Nutrimenta Sinica
1956;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of life style combined with dietary intervention on non-alcoholic fatty liver disease(NAFLD).Method One hundred and twenty five subjects of NAFLD with overweight and obesity,aged 30-60 years,were enrolled in the study from the group for physical examination in Health Administration Center of our hospital during 2006-2007.They were diagnosed to be 48 mild,70 moderate and 7 severe cases by ultrasonic tomography.A regime of dietary intervention combined with exercise was planned according to 3 d dietary survey before intervention.They were asked to follow the therapeutic menus and exercise instruction during 12 mon of the study.We followed up the subjects and gave them instructions regularly in the whole period of study.Results After 12 mon interven-tion,the body weight(BW),body mass index(BMI),waist-hip ratio(WHR),serum total cholesterol(TC),triglycerides(TG),low-density lipoprotein cholesterol(LDL-C) and alanine glutamate aminotransferase(ALT) of the subjects were decreased significantly.High density lipoprotein cholesterol(HDL-C) was not changed.By ultrasonic tomography,16% of the subjects recovered to normal,and 77 moderate to severe cases deceased to 31,with reduction rate 59.7%.Conclusion Good therapeutic effects were observed after 12 mon of dietary intervention combined with rational exercise.