Influence of nerve growth factor and aminogunidine on visual evoked potential in diabetic rats
- VernacularTitle:神经生长因子和氨基胍对糖尿病大鼠视觉诱发电位的影响
- Author:
Yan-Zhi SANG
;
Xin LIU
;
Lin LIU
;
Chun-Yan ZHAO
;
- Publication Type:Journal Article
- Keywords:
diabetes mellitus;
visual evoked potential;
nerve growth factor;
aminoguanidine
- From:
Academic Journal of Second Military Medical University
1985;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the changes of visual evoked potential(VEP)in diabetic rats and the influence of nerve growth factor(NGF)and aminoguanidine(AG)on VEP.Methods:Diabetes was induced in adult male Wistar rats with streptozotocin(STZ).Rats were divided into normal control group(CON),diabetes model group(DM).NGF-treated group(D +N)and AG-treated group(D+A).VEP was measured during the 3~(rd)month,6~(th)month,9~(th)month,and 12~(th)month.Results: Compared with the CON group,all rest groups had longer latencies and lower amplitudes(P
