Change of immunological response and cell proliferation in breast augmented by polyacrylamide hydrogel injection
- VernacularTitle:聚丙烯酰胺水凝胶注射隆乳术后乳腺组织免疫应答及细胞增殖的变化
- Author:
Rui MA
;
Zhen-Yu CHEN
;
Hui-Chao LI
;
Ji-Zhen REN
;
Zhen-Hua ZHANG
;
- Publication Type:Journal Article
- Keywords:
polyacrylamide hydrogel;
mammary glands;
CD68;
PCNA;
CD25;
cell proliferation
- From:
Academic Journal of Second Military Medical University
1985;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the change of immunological response and cell proliferation in breast tissues augmented by polyacrylamide hydrogel injection(PHI).Methods:The expression of CD68,CD25 and PCNA in 20 breast tissues with indurations,12 without indurations after breast augmentation by PHI,and 10 normal breast tissues was examined by immunohistochemistry P-V6000; analysis was also done by H-E staining.Results:Hyperplasia of fibrous tissue and infiltration of inflammatory cells and macrophages were found in the breast and adjacent tissues 3-8 years after PHI.Positive cells of CD68,CD25 and PCNA hardly existed in the normal tissues,but the breast tissues around the polyacrylamide hydrogel had many positive cells of CD68 and PCNA,especially in cases with indurations;there were significant differences between the 3 groups(P
