MicroRNAs and liver cancer:recent progress
- VernacularTitle:MicroRNAs与肝癌
- Author:
Ping YE
;
Feng-Hai YU
;
- Publication Type:Journal Article
- Keywords:
microRNA;
suppressor tumor genes;
oneogenes;
liver neoplasms
- From:
Academic Journal of Second Military Medical University
1985;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
MicroRNA(miRNA)is a small non-coding RNA that contains 21 to 23 nucleotides and can down-regulate gene expression by translational repression.Recent studies found that some miRNAs might function both as oncogenes and tumor suppressors;its role in the tumorigenesis may complement and enrich the mechanisms of tumorigenesis.Liver cancer is a great threat to human health,whose pathogenesis is still not completely understood.MiRNAs can influence the tumorigenesis,differ- entiation and treatment of liver cancer.Here we summarizes the related progression in research of miRNA and liver cancer.
