Effects of age and sex on circadian rhythms of renin-angiotensin system.
- VernacularTitle:年龄 性别对肾素-血管紧张素系统的近日节律的影响
- Author:
Mei LIU
;
Yi-Fang GUO
;
Lian-Ying NIU
;
- Publication Type:Journal Article
- Keywords:
Circadian rhythm;
Benin-angiotensin system;
Renin;
Angiotensin-convertion enzyme
- From:
Chinese Journal of Practical Internal Medicine
2006;0(S2):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effect of age and sex on circadian rhythms of renin-angiotensin system(RAS) .Methods 96 SPRD rats were divided into three groups.The levels of renin(Ren)activity,angiotensin Ⅱ(Ang Ⅱ)and angiotensin-converting-enzyme(ACE)in plasma or serum were respectively determined.Results The plasma or serum levels of renin,ACE,and angiotensin-Ⅱ in adult male group(D group)were significantly increased in comparison with elderly male group(M group)and elderly female group(F group).There were not significantly different between F group and M group in the levels of Ren activity,AngⅡ and ACE.The three substances presented typical circadian rhythms in three groups(P
