Correlation analysis between HBV Pre-S1 antigen with HBeAg and HBV DNA
- VernacularTitle:乙型肝炎病毒前S1抗原与e抗原、乙型肝炎病毒DNA的相关性分析
- Author:
Xiao-Jing HOU
;
Yan LIANG
;
Feng-Chun HE
;
Jie CHEN
;
Yan-Fang CUI
;
Ren-Qian ZHONG
;
Hao WANG
;
- Publication Type:Journal Article
- Keywords:
hepatitis B virus;
pre-S1 antigen;
e antigen;
DNA
- From:
Academic Journal of Second Military Medical University
1999;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the correlation between HBV Pre-S1 antigen,HBeAg levels and HBV DNA copies,so as to assess the clinical value of Pre-S1 in detection of HBV replication.Methods:A total of 363 HBsAg-positive samples were col- lected.The levels of Pre-S1 antigen,HBeAg and HBV DNA copies were determined by ELISA,time-resolved immuno-fluores- cent method and real-time fluorescent quantitative PCR(FQ-PCR),respectively.The correlation between the determination re- sults was analyzed.Results:Pre-S1 antigen level was correlated with the level of HBeAg(X~2=94.4,P
