More attention to be paid on diagnostic models of hepatocellular carcinoma:hint from liver fibrosis diagnostic models
- VernacularTitle:注重肝癌诊断模式研究——肝纤维化诊断模式带来的启发和思考
- Author:
Chun-Fang GAO
;
Meng-Chao WU
;
- Publication Type:Journal Article
- Keywords:
carcinoma;
hepatocellular;
diagnosis;
sensitivity;
specificity
- From:
Academic Journal of Second Military Medical University
1999;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Early diagnosis of hepatocellular carcinoma(HCC)is still a great challenge in clinical practice.Tumor markers such as alpha-fetoprotein(AFP),liver enzymes,cytokines,and some special glycoproteins,though helpful,are not sensitive and specific enough for early diagnosis of HCC.The establishment of several interesting predictive diagnostic models on liver fi- brosis/cirrhosis suggests that mathematic predictive model,which is developed based on large sample size and follow-up study, might be of higher sensitivity,specificity and feasibility in clinical application.Here we suggest that more attention should be paid to this kind of multi-parameter predictive diagnostic models clinically,so as to improve the early diagnosis of HCC in a more economical and feasible way.
