The correlation between nosocomial infections and the serum levels of interleukin-10,interleukin-13,interlenkin-15 in patients with chronic hepatic failure
- VernacularTitle:慢性肝功能衰竭患者血清白细胞介素-10、-13、-15水平变化和医院感染的相关性
- Author:
Zhi-Jun SU
;
Jian-Liang ZHUANG
;
Ru-Yi GUO
;
Xiao-Dong QIU
;
De-Song MING
;
Qi LIN
;
- Publication Type:Journal Article
- Keywords:
Hepatitis,viral,human;
Cross infection;
Interleukin-10;
Interleukin-13;
Interleukin-15;
Liver failure
- From:
Chinese Journal of Infectious Diseases
2007;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the significance of the serum levels of interleukin-10 (IL-10),IL-13,IL-15 of patients with chronic hepatic failure and the correlation between those inter- leukin levels and nosocomial infections.Methods The serum levels of IL-10,IL-13,IL-15 of 58 patients with chronic hepatic failure were measured by double antibody sandwich enzyme-linked immu- nosorbent assay at the time of admission and 2 weeks after admission.Results The serum levels of IL-15 and the propotion of IL-15/IL-10 and IL-15/IL-13 in patients with chronic hepatic failure group at the time of admission were significantly higher than those in healthy control group[(358.16?290.91) ng/L vs (38.55?21.49) ng/L,12.93?14.26 vs 1.10?0.55,98.55?97.5.5 vs 9.70?5.03,respectively,all P=0.000].Those in death group were significantly higher than those in improving group[(479.93v205.52) ng/L vs (244.51?236.29) ng/L,17.65?17.78 vs 8.53?7.98,130.69?115.50 vs 68.55?65.99,respectively,all P
