Diffusion-weighted MR imaging in benign and malignant orbital masses
- VernacularTitle:MR扩散加权成像在眼眶良恶性肿块鉴别诊断中的应用
- Author:
Jian GUO
;
Zhenchang WANG
;
Jun-Fang XIAN
;
Yan-Tao NIU
;
Bo ZHAO
;
Fei YAN
;
Zhong-Lin LIU
;
Ben-Tao YANG
;
- Publication Type:Journal Article
- Keywords:
Orbit neoplasms;
Magnetic resonance imaging;
Diffusion
- From:
Chinese Journal of Radiology
2000;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyse the characteristics of orbital benign and malignant masses on diffusion weighted imaging in combination with conventional MR imaging and evaluate the diagnostic value of apparent diffusion coefficient in distinguishing benign and malignant orbital lesions.Methods Seventy- seven cases with orbital masses,including fifty-five benign lesions and twenty-two malignant tumors,who underwent conventional MRI and diffusion imaging scanning were studied with use of a 1.5 T magnetic resonance system.Quantitative ADC measurements of masses(ADC_M)and of the white matter of eontralateral temporal lobe(ADC_W)were made with two different b-values of 0 and 1000 s/mm~2.The ADC ratio(ADCR)of the lesion to the control was calculated.The receiver operating characteristic curves(ROC) were constructed using various cut points of ADC_M and ADCR for different parameters to differentiate between benign and malignant masses.The area under the ROC curve for each parameter was also calculated. Results All cases were proved by histopathology.The mean ADC_M and ADCR of benign orbital masses were(1.56?0.75)?10~(-3)mm~2/s and 1.85?0.91,respectively.The mean ADC_M and ADCR of malignant orbital masses were(1.09?0.42)?10~(-3)mm~2/s and 1.28?0.53,respectively.There were significant difference both between ADC_M and ADCR of benign and malignant masses(t=2.803,2.735,P
