The study of expression of matrix metaUoproteinases-2 in patients with colorectal cancer
- VernacularTitle:基质金属蛋白酶在大肠癌中的表达及意义
- Author:
Ya MA
;
Guang-Ling CAI
;
Guang-Yin YU
;
Wei-Hua YIN
;
Li CHEN
;
- Publication Type:Journal Article
- Keywords:
Colorectal neoplasms;
Gelatinase B;
Immunohistochemistry
- From:
Chinese Journal of Primary Medicine and Pharmacy
2005;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective Research the correlation between expression of MMP-2 in colorectal cancer and patho- logical factors,or biological behaviors in colorectal cancer.Methods The expression of MMP-2 in 68 cases with col- orectal cancer were detected by immunohistochemical staining.Results The expression of MMP-2 in colorectal can- cer was not correlated with tumor region and histologic type,but related with depth of tumor invasion and metasta- sis.The frequency of positive cases in patients with colorectal cancer with of lymph,node metastasis was significantly higher than that in patients without lymph node metastasis(P
