COL3A1、COL1A2 Genes and Intracranial Aneurysms
- VernacularTitle:COL3A1、COL1A2基因与颅内动脉瘤
- Author:
Tao HUA
;
Ji-Zong ZHAO
;
- Publication Type:Journal Article
- Keywords:
COL3Al gene;
COLl A2 gene;
intracranial aneurysm;
genetics
- From:
International Journal of Cerebrovascular Diseases
2006;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Tae formation,development and rupture of intracranial aneurysms result from the interaction of genetic and environmental factors.The genetic mode may be nonclassical Mendelian inheritance for most patients with intracranial aneurysms.Studies have shown that COL3A1 and COLI A2 genes of the coded main extracellular matrix proteins in the arterial walls are closely associated with intracranial aneurysms.