Analysis of drug resistance in Pseudomonas aeruginosa in ICU and its characteristic of TCM syndrome
- VernacularTitle:重症监护病房铜绿假单胞菌耐药性分析及其中医证候特点
- Author:
Xiu-Jie YANG
;
Chen ZHANG
;
Wen-Sheng QI
;
Hai-Tao LAN
;
Shuo WANG
;
Yi-Xi YANG
;
Xin ZHAO
;
Xi-Lu YE
;
Rong MA
;
- Publication Type:Journal Article
- Keywords:
Pseudomonas aeruginosa;
drug resistance;
syndrome of TCM;
Characteristic
- From:
China Journal of Traditional Chinese Medicine and Pharmacy
2005;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To assess the relationship between the characteristic of drug resistance in Pseudomonas aeruginosa and the syndrome of traditional Chinese medicine(TCM)in ICU.Methods: The 73 strains of Pseudomonas aeruginosa were isolated from sputum specimenpatients of in-patients in our ICU from March 2005 to February 2006.The data of the drug sensitivity test in vitro was analysised.The relation between the syndrome of TCM and drug resistance in Pseudomonas aeruginosa was probed.Results: The 73 strains of Pseudomonas aeruginosa were drug resistant to majority kinds of anti-infective except Piperacillin-Tazobactam,Piperacillin,Cefoperazone-Sulbactam,and Amikacin.The mains syndromes of TCM of all patients infected Pseudomonas aeruginosa were deficiency-excess complex(虚实夹杂证) and excess pattern(实证)(97.26%).The mains of deficiency-excess complex(虚实夹杂证) were Qi vacuity and phlegm obstruction(气虚痰阻证)and Yin vacuity internal heat(阴虚热郁证).The mains of excess pattern(实证) were phlegm-heat(痰热郁阻证)and phlegm-stasis(痰瘀互阻证).Conclusions: Combined ?-lactam antibiotics and aminoglycoside antibiotics is the first selection to treat the multidrugresistant Pseudomonas aeruginosa.Indentifing patterns and determining treatment in TCM could be tried in the treatment of patients infected Pseudomonas aeruginosa.
