The Acting Mechanisms of Statins and Their Application in the Prevention and Treatment of Stroke
- VernacularTitle:他汀类药物作用机制及其在卒中防治中的应用
- Author:
Ding-Ming SUN
;
Zhi-Jun ZHANG
;
- Publication Type:Journal Article
- Keywords:
statins;
stroke;
subarachnoid hemorrhage;
cerebral vasospasm
- From:
International Journal of Cerebrovascular Diseases
2006;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Stroke is one of the most important causes of disability throughout the world.Epide- miological and clinical studies have demonstrated that statins significantly decrease the incidence of ischemic stroke.In addition to lipid-lowering effect,statins may also have a number of other acting mechanisms that are not dependent on reducing cholesterol levels.Moreover,statins inhibit cerebral vasospasm caused by subarachnoid hemorrhage.For most of the individuals,the safety and tolerability of statins are well.
