Minimally invasive lung volume reduction treated with bronchi occlusion emphysema model
- VernacularTitle:微创封堵法肺减容术的实验研究
- Author:
Da-Yong ZHOU
;
Li-Ming SHEN
;
Jun-Kang SHEN
;
Yi-Qi JIN
;
Lei CHEN
;
Xian-Chen HUANG
;
- Publication Type:Journal Article
- Keywords:
Pulmonary emphysema;
Radiology,interventional;
Animals,labortory
- From:
Chinese Journal of Radiology
1999;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the efficacy and feasibility of the coil-and-glue method for the reduction of lung volume in rabbit emphysema model.Methods Sixteen rabbits of emphysema model were divided into the occlusion group(n=10),in which both anterior bronchi were occluded using the coil-and- glue method,and the control group(n=6).The maximal static pressure of airway(P_(max)),peak expiratory flow(PEF),end-expiratory volume(EEV)and pressure of oxygen(PO_2)were measured at ante- emphysema,post-emphysema,1 week and 4 week after occlusion respectively.The expectoration(or migration)of coil and collapse of lung were also investigated.Results P_(max)was(20.0?1.3)and(17.1? 1.4)cm H_2O(1 cm H_2O=0.098 kPa)in the occlusion group at ante-emphysema and post-emphysema respectively.P_(max)was(19.2?1.4)cm H_2O in the occlusion group in the 1 week after the occlusion,while (17.1?1.5)cm H_2O in the control group(F=6.68,P
