Effects of quetiapine and risperidone in the treatment of behavior and psychiatric symptom of dementia
- VernacularTitle:奎硫平与利培酮治疗痴呆患者行为与精神障碍的对照研究
- Author:
Tao LOU
;
Ning LI
;
Chuan-Sheng WANG
;
Zhi-Feng ZHANG
;
Jian-Ying WANG
;
- Publication Type:Journal Article
- Keywords:
Quetiapine;
Risperidone;
Dementia;
Behavior and psychiatric symptom of dementia
- From:
Chinese Journal of Primary Medicine and Pharmacy
2006;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of quetiapine and risperidone in the treatment of behavior and psychiatric symptom of dementia(BPSD).Methods 56 cases of Alzheimer's disease and vascular dementia pa- tients were all met for the classification and diagnostic criteria for mental illness in China(CCMD-3)and randomly divided into two groups(27 in quetiapine group,29 in risperidone group),experimental dosage were 0.05～0.3g/d and 1～2mg/d,respectively.The treatment lasted for 8 weeks.Results The total efficiency of quetiapine was 66.67% and that of risperidone was 65.5%,and the statistical difference was significant.As for the adverse effects, there was no significant difference,but incidence of EPS in quetiapine group was less than that of risperidone group. Conclusion Quetiapine can be widely administrated in clinic application as the high efficacy of control BPSD with low minor adverse effect.
