Clinical Study of Honghua Injection Plus Prednisone and Cyclophosphamine Treatment on Refractory Nephrotic Syndrome
- VernacularTitle:红花注射液联合激素和环磷酰胺治疗难治性肾病综合征
- Author:
Xiuzhen ZHAO
;
Ruixia MA
;
- Publication Type:Journal Article
- Keywords:
refractory nephrotic syndrome;
Honghua injection;
prednisone;
cyclophosphamide
- From:
Journal of Zhejiang Chinese Medical University
2006;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
[Objective] To investigate the therapeutic effect of Honghua injection plus prednisone and cyclophosphamine on refractory nephrotic syndrom.[Methods] 38 patients with refractory nephrotic syndrom were given intravenous Honghua and cyclophosphamine plus oral prednisone.Serum total cholesterol,triglyceride,liver and renal function,blood routine test,24h protennuria were observed.[Results] Total effective ratio was 92.1%.Cure ratio was 73.68%.Partly cure ratio was 18.42% and ineffective ratio was 7.89%.[Conclusions] Patients with refractory nephrotic syndrom were treated by Honghua injection plus prednisone and cyclophosphamine,which could reduce the application of prednisone,its side effects and enforce its therapeutic effect.What is more,this treatment could lessen therapeutic process,prevent relapse and recoil,protect effectively the retreat syndrom of prednisone as well.