A study of dynamic changes of NO,NOS in serum and CSF in patients with CNS infection
- VernacularTitle:不同病原体中枢神经系统感染患者血清和脑脊液中一氧化氮总一氧化氮合酶的动态变化
- Author:
Pei LIU
;
Fan-Yuan KONG
;
Ruo-Fen WU
;
Li LI
;
Yue-Ying PAN
;
- Publication Type:Journal Article
- Keywords:
Meningioma;
Nitric oxide;
Nitric-oxide synthase
- From:
Chinese Journal of Primary Medicine and Pharmacy
2006;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the dynamic changes of NO,NOS in serum and CSF in patients with CNS infection and lay an experimental basis for discrimination of CNS infection due to different agents.Methods The method of nitrate redutase and the method of chromometry were employed to measure NO,NOS in serum and CSF at different time.The dynamic changes of NO,NOS in serum were observed on admission,on 3,5,9,14 day after admission.The dynamic changes of NO,NOS in CSF before treatment and two weeks after treatment were ob- served,too.Results There were no difference between the the concentration of NO and the vigor of total NOS in serum and in CSF of viral meningitis,bacterial meningitis and tubercular meningitis patients due to different agents. Conclusion The changes of the concentration of NO in serum and CSF,the vigor of total NOS in serum and CSF could not he seen as laboratory basis for discrimination of CNS infection due to different agents.
