Expression of integrin?_3 and integrin ?_1 in breast cancer and its clinical significance
- VernacularTitle:整合素?_3?_1在乳腺癌中的表达及其临床意义
- Author:
Ting-Jian LI
;
Fei-Ran ZHANG
;
Jie-Xiong HUANG
;
Sheng-Ping HU
;
Pei-Yan WU
;
Guang HOU
;
- Publication Type:Journal Article
- Keywords:
Inregrins;
Breast neoplasms;
Immunohistochemical assay
- From:
Chinese Journal of Primary Medicine and Pharmacy
2006;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the expression of inregrin?_3 and integrin?_1 in breast cancer and its bio- logical significance.Methods Immunohistochemical assay was used to determine the expression of integrin?_3 and integrin?_1 in the breast cancer(32 cases).Results In normal breast tissue,the positive expression rates of integrin?_3 and integrin?_1 were 0 % and 25 %.In the breast cancer tissue,the positive expression rates of integrin?_3 and inte- grin?_1 were 36 % and 81%.Conclusion The integrin?_3 and integrin?_1 are close associated with the biological sig- nificance of breast cancer.To examine its expression is useful to evaluate the aggressive degree,metastatic potential and prognosis in patients with breast cancer.
