Study of Effect of Weixikang Apozema on Growth Factor of Acetic Acid Gastric Ulcer Rats
- VernacularTitle:胃喜康煎剂对乙酸致胃溃疡大鼠细胞生长因子的影响
- Author:
Jian-Ping LIU
;
Dong-Ju HU
;
- Publication Type:Journal Article
- Keywords:
Gastric ulcer;
TCM Therapy;
Weixikang;
Growth factor;
Animal experimental study
- From:
China Journal of Traditional Chinese Medicine and Pharmacy
2005;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To observe the effect of Weixikang apozema on growth factor of acetic acid gastric ulcer rats.Methods: The rats were divided into blank control group(abbreviated as blank group),model group,ranitidine group,Weixikang low dosage group(abbreviated as low dosage group) and Weixikang high dosage group(abbreviated as high dosage group) at random,each group has 8 rats.The content of epidermal growth factor(EGF) and transforming growth factor-?(TGF-?) were measured with radioimmunoassay.The protein expression of EGF,TGF? and EGFR were measured with immunohistochemical method.Results: The content of EGF and TGF-? and the protein expression of EGF,TGF-? and EGFR in low dosage group and high dosage group have increased(P
