Study on clinical features and prognostic factors in acquired immune deficiency syndrome patients with opportunistic infections in Shanghai
- VernacularTitle:上海地区艾滋病患者机会性感染的临床特征和影响预后的因素
- Author:
Hong-Qing SUN
;
Shan-Ming WU
;
Liang CHEN
;
Jie DONG
;
Qin HUANG
;
Wei-Ming XU
;
- Publication Type:Journal Article
- Keywords:
Acquired immunodeficiency syndrome;
AIDS-related opportunistic infection;
Prognosis;
CD4 lymphocyte count
- From:
Chinese Journal of Infectious Diseases
2007;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate clinical features and prognostic factors in acquired immune deficiency syndrome (AIDS) patients with opportunistic infections.Methods Forty-two cases of AIDS patients with opportunistic infections were enrolled in this study.Clinical data and major factors affecting the prognosis were analyzed using Logistic regression.Results Bacterial infection was the first etiological factor(57.1%) of opportunistic infections in AIDS patients.Eighty-three point three percent of patients infected with more than two kind of etiological agents.Fifty-seven point one per- cent of cases were infected in multiple sites.CD4~+ T cells count was associated with the opportunistic infections.Conclusions The CD4~- T lymphocytes count is the key factor affecting the prognosis of AIDS patients with opportunistic infections.The average of CD4~+ T lymphocytes count is significant- ly related with the major opportunistic infections in AIDS paitents.
