MRI features of patients with heroin spongiform leukoencephalopathy of different clinical stages
- VernacularTitle:不同临床分期海洛因海绵状白质脑病患者的头颅MRI特征
- Author:
Zhu SHI
;
Su-Yue PAN
;
Liang ZHOU
;
Zhao DONG
;
Bing-Xun LU
;
- Publication Type:Journal Article
- Keywords:
Heroin;
Nervous system diseases;
Magnetic reasonce imaging
- From:
Chinese Journal of Radiology
2001;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate radiological features of patients with heroin spongiform leukoencephalopathy(HSLE)of different clinical stages and discuss the evolutional characteristics of the disease.Methods Thirty two patients with HSLE underwent precontrast MRI and postcontrast MRI.The history of addiction,clinical presentations,and brain MRI were analyzed and summarized according to the patient's clinical staging.There are 6 cases in Ⅰ stage,21 cases in Ⅱ stage,5 cases in Ⅲ stage.Results All patients had history of heroin vapor inhalation.Most of the cases developed subacute cerebellar impairment in earlier period.Brain MRI revealed symmetrical lesion within bilateral cerebellum in all patients.Splenium of the corpus callosum,posterior limb of the internal capsule,deep white matter of the occipital and parietal lobes,were gradually involved with progressive deterioration of HSLE.The brain stem and deep white matter of the frontal and temporal lobes were involved in some cases.Conclusions The history of heated heroin vapor inhalation was the prerequisite for the diagnosis of HSLE.Brain MRI presented the characteristic lesion and its evolution of HSLE.Brain MRI was very important for accurate diagnosis and helpful to judge the clinical stages according to the involved brain region.
