Clinical analysis about 5 cases of actinomycete keratitis
- VernacularTitle:放线菌性角膜炎5例临床分析
- Author:
Xiao-Tang YIN
;
Shi-Yun LUO
;
Ran LI
;
Shi-Jing DENG
;
Zhi-Qun WANG
;
Xiu-Ying JIN
;
Xu-Guang SUN
;
- Publication Type:Journal Article
- Keywords:
actinomycete keratitis/diagnosis;
actinomycete keratitis/management
- From:Ophthalmology in China
1993;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze clinical diagnosis and management of 5 patients with actinomycete keratitis.Design Retro- spective case series.Participants 5 patients (5 eyes) with actinomycete keratitis.Methods The clinical features and microbiologic da- ta of 5 culture-proven cases of actinomycete keratitis recorded between October 2004 to March 2006 were analyzed.Main Outcome Measures clinical characteristics,isolations identification,drug susceptibility test and treatments.Results All patients were males and farmers.Of the 5 cases presented in this study,4 cases were followed by minor trauma as a predominant risk factor,and were pre- sented by a chronic progressive corneal ulcer with a wreath pattern of infiltrate.The diagnosis of all cases was based on laboratory in- vestigations,by which 4 cases of nocardia and one case of streptomyce were identified.A variable drug sensitivities were presented in nocardia isolates,which including TMP-SMZ,amicasin,gentamicin and fluorine-quinolones.Conclusions Nocardia keratitis is mainly followed by a minor trauma.It is identified predominantly by laboratory investigations.Tropical and systemically sensitive biotic are the initial choice,while debridement and amnionic transplantation could be an effective alternative.
