Sebaceous carcinoma of the eyelid:a clinicopathological study
- VernacularTitle:67例眼睑皮脂腺腺癌临床特征及组织病理学分析
- Author:
Zhe ZHANG
;
Bin LI
;
Fei GAO
;
Xiao-Lin XU
;
Liao-Qing LI
;
- Publication Type:Journal Article
- Keywords:
sebaceous carcinoma/diagnosis;
clinical features;
histopathological features
- From:
Ophthalmology in China
1993;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To review the clinical and histopathological features,management and outcomes in 67 patients with seba- ceous carcinoma of the eyelid.Design Retrospective case series.Participants Sixty-seven cases of the sebaceous gland carcinoma were retrieved from the ophthalmology archives of Tongren Hospital between 1996 and 2005.Methods Clinical data of all patients were re- viewed from the charts.Pathology specimens were reviewed in all cases.Main Outcome Measure Presenting features,sites of origin, location,differentiation,management,histopathologic findings,and incidence of recurrence in 67 patients.Results A total of 36 female and 31 male patients were identified.The mean age at diagnosis was 59 years (range from 35 to 84).Initial clinical diagnoses elsewhere were sebaceous carcinoma (43.28%),chalazion (25.37%),basal cell carcinoma(7.46%).Initial histopathologic diagnoses were sebaceous carcinoma(79.10%),basal cell carcinoma(5.97%),squamous cell carcinoma(1.49%) and other or not available(4.48%).The initial treat- ment involved excisional techniques with reconstruction in 42 cases,anti-inflammatory in 12 cases,without any treatment in 10 cases. 61.19% cases presented the pagetoid invasion.Local recurrence developed in 58.21% and two died from metastatic sebaceous carcino- ma (8.70%).Regional lymph node excision was performed in 13.04% because of local metastases.Five year survival rate was 94.87%. Conclusions About 1/3 cases had not receive the right treatment at initial diagnosis eyelid.The recurrence rate of patients was still high.
