The comparing research of anticoagulation with sodium citrate or heparin in continuous venovenous hemodiafil- tration.
- VernacularTitle:连续性静脉静脉血液透析滤过治疗中肝素抗凝与体外枸橼酸钠抗凝的对比研究
- Author:
Xiao-Mao LIN
;
Zhi-Mei QIN
;
Liang CHEN
;
Al ET
;
- Publication Type:Journal Article
- Keywords:
Heparin;
Sodium citrate;
Continuous venovenous hemodiafiltration
- From:
Chinese Journal of Practical Internal Medicine
2006;0(S1):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the anticoagultive effectiveness and specialty of sodium citrate comparing with hep- arin in continuous venovenous hemodiafiltration (CVVHDF).Methods 50 multiple organ disorder patients undergoing CWHDF were randomly divided into two groups:group A(sodium citrate)27 cases,group B(heparin)23 cases,blood e- lectrolyte,acid-alkali degree,cruor index changes,the blood coagulation of tube path way and blood filter were recor- ded.As the same time,side effects were observed in theraphy.Results The patients of two groups were kept stable vital signs,serum electrolyte and blood gas markers during the therapeutic periods.Moreover,ideal serum creatinine and urea clearance rate and uhrafiltration rate were obtained in all patients.The coagulation and longevity of blood filter of Group A are better than Group B,Group A without sigaificantly prolonged cruor index inside body,the dosage of calcium gluco- nate in Group A are greater than Group B.Conclusion Out body anticongulation of sodium citrate is more effective and reliable than regular heparin anticoagulation.
