Establishment of Chloasma Mouse Model with Syndrome of Liver-qi Stagnation and Comparative Study of It with Existent Models
- VernacularTitle:肝郁型黄褐斑小鼠模型的建立及其与现有模型的比较研究
- Author:
Nanyue WANG
;
Jiaxu CHEN
;
Xiaodan WU
;
- Publication Type:Journal Article
- Keywords:
chloasma;
syndrome of liver-qi stagnation;
mouse model
- From:
China Journal of Traditional Chinese Medicine and Pharmacy
2005;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To establish and authenticate the chloasma mouse model with syndrome of liver-qi stagnation,and compare it with other existent models.Method: After the injection of progesterone,chronically constrained them and gave them partially ultraviolet radiation.Results: Multiple models of progesterone injection and ultraviolet radiation compounding with chronic constraint can heighten MDA,depress SOD,and increase melanocytes of skin.Meanwhile,the ethology of this model showed it's syndrome of liver-qi stagnation.Conclusion: The multiple factor chloasma mouse model of liver-qi stagnation syndrome has been built successfully.
