Effects of Saussurea Involucrata Culture on Mouse Immune Function
- VernacularTitle:天山雪莲培养物对小鼠免疫功能的影响
- Author:
Jingming JIA
;
Chunfu WU
;
- Publication Type:Journal Article
- Keywords:
Saussurea involucrate;
tissue culture;
immune function
- From:
China Journal of Traditional Chinese Medicine and Pharmacy
2005;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:The tissue culture of Saussurea involucrata has been studied for the protection of immune function activities in animal models in our research.Methods: The tissue culture of S.involucrata at the doses of 75,150 and 300mg/kg were given to mice by intragastric administration,successive medication for 7 days,and then the effects of S.involucrata were investigated in mice by carbon clearance rate,DNCB induced delayed hypersensitivity and serum hemolysin formation.Results: The tissue culture of S.involucrata at the doses of 150mg/kg i.g.,for 7 days could inhibit the non-specificity of immune function in mice.At the doses of 300mg/kg i.g.,for 7 days it could have significantly inhibitory effect on delayed hypersensitivity in mice and increase the humoral immunity activity in mice.Conclusion: The tissue culture of S.involucrata had the protection effect on immune function activities.
